The NMPE pReference® frameless approach to stereotactic radiosurgery offers several crucial advantages over frame-based stereotaxis. Foremost is real-time, image-guided localization and target verification, providing documented, independently confirmed, sub-millimeter accuracy for every setup. In contrast, stereotactic systems employing a relocatable frame and room lasers have a reported accuracy of 3 - 4 mm.

Another key advantage is elimination of the need to complete the entire treatment in a single day, allowing each stage to be scheduled at the convenience of the patient and staff.

The frameless technique introduces and facilitates the widely documented advantages of fractionation.

Treatment planning with the pReference system offers a significant advantage in clinical support, stemming from the NMPE centralized radiotherapy treatment planning facility which has planned over 1000 cases since the late 1980’s. An online clinical database provides details on over 800 stereotactic cases representing 45 histologies.

The following pages describe NMPE’s two, cost-effective frameless SRS alternatives: Electronic Remote Planning, for extensive off-site support and limitation of capital outlay; and the Comprehensive System, for a complete, turn-key solution supported by on-line plan review. The Windows® 2000-based 3D software delivers state-of-the-art display for easy and accurate treatment planning.